Cardiometabolic Management Essentials for Advanced Practice Providers (APPs)-Lipid Assessment and Management

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Video Summary

Lipid management is important for reducing the incidence of cardiovascular disease and atherosclerotic cardiovascular events. Atherosclerosis is an inflammatory disease, and lipoproteins such as low-density lipoprotein cholesterol (LDL-C) have been associated with the development of atherosclerosis. Understanding lipid targets and treatment strategies, as well as identifying additional cardiovascular risk factors, is critical for reducing the incidence of cardiovascular disease. Lipid assessment involves measuring total cholesterol, HDL cholesterol, triglycerides, LDL cholesterol, and non-HDL cholesterol. Hypercholesterolemia is defined as LDL cholesterol greater than or equal to 130 mg/dL. The use of statins is recommended as the first line of treatment for lipid management. Statins work by inhibiting cholesterol biosynthesis and increasing the number of LDL cholesterol receptors. Other non-statin therapies include ezetimibe, PCSK9 inhibitor monoclonal antibodies, bempedoic acid, inclisiran, and icosapent ethyl. Lifestyle modifications such as diet and exercise are also important in managing lipid levels. Screening for lipid disorders should begin at a young age, and treatment should be individualized based on each patient's risk factors and goals. It is important to monitor lipid levels regularly and adjust treatment as needed to help reduce the risk of cardiovascular disease.

Keywords

lipid management

cardiovascular disease

atherosclerosis

LDL cholesterol

hypercholesterolemia

statins

non-statin therapies

lifestyle modifications

screening for lipid disorders

reduce cardiovascular disease risk